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Changing the way we diagnose

Let us help you diagnose the precise systems that are causing your patient's chronic inflammatory response syndrome (CIRS).

CIRS has multiple sources including: exposure to environmental sources of biotoxins; chronic illness from Lyme disease present even after treatment with antibiotics. The exposure to environmental sources of biotoxins includes a chronic exposure to the interior environment of water-damaged buildings (WDB) or ingestion of fish contaminated with the toxins of marine dinoflagellates, such as ciguatoxins.

Patients with CIRS are often misdiagnosed as having depression, stress, allergy, fibromyalgia, post-traumatic stress disorder, Chronic Fatigue Syndrome, somatization, etc., and are treated with various therapies, some of which have not yet been shown to be effective and are costly.

CIRS is often misdiagnosed because,
UNTIL NOW there have been no confirmatory clinical assays.
Our protocol results in comprehensive information based on a proteogenomic analysis that identifies proteins and genes that, in subjects suffering from CIRS, are differentially expressed compared to healthy subjects.

With Progene DX, you can see what is happening at the gene transcription level so you can target your treatment.

Progene DX only sells to licensed and registered physicians or other qualified healthcare providers in the United States.

By placing an order on our website you confirm that you are a physician or other qualified healthcare provider licensed to practice in the United States.


1. This assay is being performed for Research Use Only; it is not for use in diagnostic procedures.
2. This assay has been ordered by the patient's physician or other health care professional who is licenced to practice in the United States and has medical malpractice insurance.
3. This assay has no diagnosis, CPT or ICD-10 code and will not be acceptable for reimbursement by Medicare, Medicaid or private insurance.
4. The patient is aware that their health care provider will forward to Progene DX de-identified personal health information (by removing the patient's name, address, SSN or any personally identifiable information as defined by HIPAA) including but not limited to environmental testing, diagnostic test results and cardiovascular studies. The patient is aware this information will be kept locked away from view of all others, with password protection for any and all information placed on a digital file.
5. By ordering this assay, the client confirms they understand and agree with these terms and Progene DX's full terms of service available at